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Identification of 12/15-lipoxygenase as a suppressor of myeloproliferative disease
Though Abl inhibitors are often successful therapies for the initial stages of chronic myelogenous leukemia (CML), refractory cases highlight the need for novel molecular insights. We demonstrate that mice deficient in the enzyme 12/15-lipoxygenase (12/15-LO) develop a myeloproliferative disorder (M...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118138/ https://ncbi.nlm.nih.gov/pubmed/17043146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061444 |
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