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Identification of 12/15-lipoxygenase as a suppressor of myeloproliferative disease
Though Abl inhibitors are often successful therapies for the initial stages of chronic myelogenous leukemia (CML), refractory cases highlight the need for novel molecular insights. We demonstrate that mice deficient in the enzyme 12/15-lipoxygenase (12/15-LO) develop a myeloproliferative disorder (M...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2006
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118138/ https://ncbi.nlm.nih.gov/pubmed/17043146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061444 |
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