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Irf8-driven myeloid differentiation is regulated by 12/15-lipoxygenase-mediated redox signaling

OBJECTIVES: Several transcription factors determine the cell fate decision between granulocytes and monocytes, but the upstream signal transduction pathways that govern myelopoiesis are largely unknown. Based on our observation of aberrant myeloid cell representation in hematopoietic tissues of 12/1...

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Detalhes bibliográficos
Main Authors: Kinder, Michelle, Thompson, James E., Wei, Cong, Shelat, Suresh G., Blair, Ian A., Carroll, Martin, Puré, Ellen
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963586/
https://ncbi.nlm.nih.gov/pubmed/20647030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2010.07.004
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