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Irf8-driven myeloid differentiation is regulated by 12/15-lipoxygenase-mediated redox signaling

OBJECTIVES: Several transcription factors determine the cell fate decision between granulocytes and monocytes, but the upstream signal transduction pathways that govern myelopoiesis are largely unknown. Based on our observation of aberrant myeloid cell representation in hematopoietic tissues of 12/1...

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Bibliographic Details
Main Authors: Kinder, Michelle, Thompson, James E., Wei, Cong, Shelat, Suresh G., Blair, Ian A., Carroll, Martin, Puré, Ellen
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963586/
https://ncbi.nlm.nih.gov/pubmed/20647030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2010.07.004
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