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Interleukin-10 and Pathogenesis of Murine Ocular Toxoplasmosis

To understand the role of interleukin-10 (IL-10) in ocular toxoplasmosis, we compared C57BL/6 (B6) and BALB/c background mice lacking a functional IL-10 gene (IL-10(−/−)) and B6 transgenic mice expressing IL-10 under the control of the IL-2 promoter. Increased cellular infiltration and necrosis were...

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Autori principali: Lu, Fangli, Huang, Shiguang, Kasper, Lloyd H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC308941/
https://ncbi.nlm.nih.gov/pubmed/14638808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.12.7159-7163.2003
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