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The IgG-specific endoglycosidase EndoS inhibits both cellular and complement-mediated autoimmune hemolysis
EndoS from Streptococcus pyogenes is an immunomodulating enzyme that specifically hydrolyzes glycans from human immunoglobulin G and thereby affects antibody effector functions. Autoimmune hemolytic anemia is caused by antibody-mediated red blood cell (RBC) destruction and often resists treatment wi...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890147/ https://ncbi.nlm.nih.gov/pubmed/20357243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-239020 |
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