The IgG-specific endoglycosidase EndoS inhibits both cellular and complement-mediated autoimmune hemolysis

EndoS from Streptococcus pyogenes is an immunomodulating enzyme that specifically hydrolyzes glycans from human immunoglobulin G and thereby affects antibody effector functions. Autoimmune hemolytic anemia is caused by antibody-mediated red blood cell (RBC) destruction and often resists treatment wi...

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Bibliografske podrobnosti
Main Authors: Allhorn, Maria, Briceño, Juana G., Baudino, Lucie, Lood, Christian, Olsson, Martin L., Izui, Shozo, Collin, Mattias
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2010
Teme:
Red Cells, Iron, and Erythropoiesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890147/
https://ncbi.nlm.nih.gov/pubmed/20357243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-239020
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