Study of the IgG endoglycosidase EndoS in group A streptococcal phagocyte resistance and virulence

BACKGROUND: The secreted enzyme EndoS, an endoglycosidase from Streptococcus pyogenes, hydrolyzes the N-linked glycan of the constant region of immunoglobulin G (IgG) heavy chain and renders the antibody unable to interact with Fc receptors and elicit effector functions. In this study we couple targ...

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Hauptverfasser: Sjögren, Jonathan, Okumura, Cheryl YM, Collin, Mattias, Nizet, Victor, Hollands, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125321/
https://ncbi.nlm.nih.gov/pubmed/21619648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-11-120
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