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Processing of Tumor Antigen Differentially Impacts the Development of Helper and Effector CD4(+) T-cell Responses

CD4(+) T cells contribute to the antitumor T-cell response as both effectors that promote tumor rejection and helpers that facilitate the activation of other antitumor effector cells, such as CD8(+) T cells. Maximal engagement of both effector and helper CD4(+) T-cell responses is a desirable attrib...

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Detalhes bibliográficos
Main Authors: Bernard, Dannie, Ventresca, Michael S, Marshall, Laura A, Evelegh, Carole, Wan, Yonghong, Bramson, Jonathan L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889742/
https://ncbi.nlm.nih.gov/pubmed/20179673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.30
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