Dendritic cell-restricted antigen presentation initiates the Follicular Helper T cell program but cannot complete ultimate effector differentiation

Follicular Helper T cells (T(FH)) are critical for germinal center (GC) formation. The processes that drive their generation and effector potential remain unclear. Here, we define requirements for MHCII antigen presenting cells (APCs) in murine T(FH) formation by either transiently ablating or restr...

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Autori principali: Goenka, Radhika, Barnett, Lisa G., Silver, Jonathan S., O’Neill, Patrick J., Hunter, Christopher A., Cancro, Michael P., Laufer, Terri M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171798/
https://ncbi.nlm.nih.gov/pubmed/21715693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100853
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