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Dendritic cell-restricted antigen presentation initiates the Follicular Helper T cell program but cannot complete ultimate effector differentiation

Follicular Helper T cells (T(FH)) are critical for germinal center (GC) formation. The processes that drive their generation and effector potential remain unclear. Here, we define requirements for MHCII antigen presenting cells (APCs) in murine T(FH) formation by either transiently ablating or restr...

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Sonraí Bibleagrafaíochta
Main Authors: Goenka, Radhika, Barnett, Lisa G., Silver, Jonathan S., O’Neill, Patrick J., Hunter, Christopher A., Cancro, Michael P., Laufer, Terri M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171798/
https://ncbi.nlm.nih.gov/pubmed/21715693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100853
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