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Antigen-sensitized CD4(+)CD62L(low )memory/effector T helper 2 cells can induce airway hyperresponsiveness in an antigen free setting

BACKGROUND: Airway hyperresponsiveness (AHR) is one of the most prominent features of asthma, however, precise mechanisms for its induction have not been fully elucidated. We previously reported that systemic antigen sensitization alone directly induces AHR before development of eosinophilic airway...

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Bibliografiska uppgifter
Huvudupphovsmän: Nakagome, Kazuyuki, Dohi, Makoto, Okunishi, Katsuhide, To, Yasuo, Sato, Atsushi, Komagata, Yoshinori, Nagatani, Katsuya, Tanaka, Ryoichi, Yamamoto, Kazuhiko
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2005
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180472/
https://ncbi.nlm.nih.gov/pubmed/15921525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-46
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