Helper-independent piggyBac plasmids for gene delivery approaches: Strategies for avoiding potential genotoxic effects

Efficient integration of functional genes is an essential prerequisite for successful gene delivery such as cell transfection, animal transgenesis, and gene therapy. Gene delivery strategies based on viral vectors are currently the most efficient. However, limited cargo capacity, host immune respons...

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Detalhes bibliográficos
Main Authors: Urschitz, Johann, Kawasumi, Miyuri, Owens, Jesse, Morozumi, Kazuto, Yamashiro, Hideaki, Stoytchev, Ilko, Marh, Joel, Dee, James A., Kawamoto, Kris, Coates, Craig J., Kaminski, Joseph M., Pelczar, Pawel, Yanagimachi, Ryuzo, Moisyadi, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889585/
https://ncbi.nlm.nih.gov/pubmed/20404201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003674107
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