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Mutant SOD1 G93A microglia have an inflammatory phenotype and elevated production of MCP-1
The inflammatory response in amyotrophic lateral sclerosis (ALS) is well documented but the underlying cellular mechanisms have not been fully elucidated. We report that microglia isolated from the mutant human SOD1 G93A transgenic mouse model of ALS, have an increased response to the inflammatory s...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889291/ https://ncbi.nlm.nih.gov/pubmed/19752764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e328331e8fa |
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