Single residue within the antigen translocation complex TAP controls the epitope repertoire by stabilizing a receptive conformation

The recognition of virus infected or malignantly transformed cells by cytotoxic T lymphocytes critically depends on the transporter associated with antigen processing (TAP), which delivers proteasomal degradation products into the endoplasmic reticulum lumen for subsequent loading of major histocomp...

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Bibliografiska uppgifter
Huvudupphovsmän: Baldauf, Christoph, Schrodt, Susanne, Herget, Meike, Koch, Joachim, Tampé, Robert
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889111/
https://ncbi.nlm.nih.gov/pubmed/20439763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001308107
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