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Ultrasensitive quantification of TAP-dependent antigen compartmentalization in scarce primary immune cell subsets

Presentation of peptides on major histocompatibility complex class I (MHC I) is essential for the establishment and maintenance of self-tolerance, priming of antigen-specific CD8(+) T cells and the exertion of several T-cell effector functions. Cytosolic proteasomes continuously degrade proteins int...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Fischbach, Hanna, Döring, Marius, Nikles, Daphne, Lehnert, Elisa, Baldauf, Christoph, Kalinke, Ulrich, Tampé, Robert
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Pub. Group 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347055/
https://ncbi.nlm.nih.gov/pubmed/25656091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7199
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