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Ultrasensitive quantification of TAP-dependent antigen compartmentalization in scarce primary immune cell subsets
Presentation of peptides on major histocompatibility complex class I (MHC I) is essential for the establishment and maintenance of self-tolerance, priming of antigen-specific CD8(+) T cells and the exertion of several T-cell effector functions. Cytosolic proteasomes continuously degrade proteins int...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Pub. Group
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347055/ https://ncbi.nlm.nih.gov/pubmed/25656091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7199 |
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