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Single residue within the antigen translocation complex TAP controls the epitope repertoire by stabilizing a receptive conformation
The recognition of virus infected or malignantly transformed cells by cytotoxic T lymphocytes critically depends on the transporter associated with antigen processing (TAP), which delivers proteasomal degradation products into the endoplasmic reticulum lumen for subsequent loading of major histocomp...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889111/ https://ncbi.nlm.nih.gov/pubmed/20439763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001308107 |
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