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A dual inhibition mechanism of herpesviral ICP47 arresting a conformationally thermostable TAP complex
As a centerpiece of antigen processing, the ATP-binding cassette transporter associated with antigen processing (TAP) became a main target for viral immune evasion. The herpesviral ICP47 inhibits TAP function, thereby suppressing an adaptive immune response. Here, we report on a thermostable ICP47-T...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5109273/ https://ncbi.nlm.nih.gov/pubmed/27845362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36907 |
| Oznake: |
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