Herpes Simplex Virus Type 2 ICP47 Inhibits Human TAP but Not Mouse TAP

Herpes simplex virus serotype 1 (HSV-1) expresses an immediate-early protein, ICP47, that effectively blocks the major histocompatibility complex class I antigen presentation pathway. HSV-1 ICP47 (ICP47-1) binds with high affinity to the human transporter associated with antigen presentation (TAP) a...

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Detalhes bibliográficos
Main Authors: Tomazin, Roman, van Schoot, Nico E. G., Goldsmith, Kim, Jugovic, Pieter, Sempé, Pascal, Früh, Klaus, Johnson, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109564/
https://ncbi.nlm.nih.gov/pubmed/9499125
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