Immunization with a Single Major Histocompatibility Complex Class I-Restricted Cytotoxic T-Lymphocyte Recognition Epitope of Herpes Simplex Virus Type 2 Confers Protective Immunity

We have evaluated the potential of conferring protective immunity to herpes simplex virus type 2 (HSV-2) by selectively inducing an HSV-specific CD8(+) cytotoxic T-lymphocyte (CTL) response directed against a single major histocompatibility complex class I-restricted CTL recognition epitope. We gene...

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Main Authors: Blaney, Joseph E., Nobusawa, Eri, Brehm, Michael A., Bonneau, Robert H., Mylin, Lawrence M., Fu, Tong-Ming, Kawaoka, Yoshihiro, Tevethia, Satvir S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Viral Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110466/
https://ncbi.nlm.nih.gov/pubmed/9811690
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