Stable binding of the herpes simplex virus ICP47 protein to the peptide binding site of TAP.

The herpes simplex virus (HSV) ICP47 protein inhibits the MHC class I antigen presentation pathway by inhibiting the transporter associated with antigen presentation (TAP) which translocates peptides across the endoplasmic reticulum membrane. At present, ICP47 is the only inhibitor of TAP. Here, we...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tomazin, R, Hill, A B, Jugovic, P, York, I, van Endert, P, Ploegh, H L, Andrews, D W, Johnson, D C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1996
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC451888/
https://ncbi.nlm.nih.gov/pubmed/8670826
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