Purification and Reconstitution of the Antigen Transport Complex TAP: A PREREQUISITE FOR DETERMINATION OF PEPTIDE STOICHIOMETRY AND ATP HYDROLYSIS

The transporter associated with antigen processing (TAP) is an essential machine of the adaptive immune system that translocates antigenic peptides from the cytosol into the endoplasmic reticulum lumen for loading of major histocompatibility class I molecules. To examine this ABC transport complex i...

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Bibliografiska uppgifter
Huvudupphovsmän: Herget, Meike, Kreiβig, Nina, Kolbe, Christian, Schölz, Christian, Tampé, Robert, Abele, Rupert
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2009
Ämnen:
Membrane Transport, Structure, Function, and Biogenesis
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797143/
https://ncbi.nlm.nih.gov/pubmed/19808685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.047779
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