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Identification of select glucocorticoids as Smoothened agonists: Potential utility for regenerative medicine
Regenerative medicine holds the promise of replacing damaged tissues largely by stem cell activation. Hedgehog signaling through the plasma membrane receptor Smoothened (Smo) is an important process for regulating stem cell proliferation. The development of Hedgehog-related therapies has been impede...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889058/ https://ncbi.nlm.nih.gov/pubmed/20439738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910712107 |
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