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Identification of select glucocorticoids as Smoothened agonists: Potential utility for regenerative medicine

Regenerative medicine holds the promise of replacing damaged tissues largely by stem cell activation. Hedgehog signaling through the plasma membrane receptor Smoothened (Smo) is an important process for regulating stem cell proliferation. The development of Hedgehog-related therapies has been impede...

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Detalhes bibliográficos
Main Authors: Wang, Jiangbo, Lu, Jiuyi, Bond, Michael C., Chen, Minyong, Ren, Xiu-Rong, Lyerly, H. Kim, Barak, Larry S., Chen, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889058/
https://ncbi.nlm.nih.gov/pubmed/20439738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910712107
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