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Molecular Cloning and Heterologous Expression of the Dehydrophos Biosynthetic Gene Cluster

Dehydrophos is a vinyl phosphonate tripeptide produced by Streptomyces luridus with demonstrated broad spectrum antibiotic activity. To identify genes necessary for biosynthesis of this unusual compound we screened a fosmid library of S. luridus for the presence of the phosphoenolpyruvate mutase gen...

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Detalhes bibliográficos
Main Authors: Circello, Benjamin T., Eliot, Andrew C., Lee, Jin-Hee, van der Donk, Wilfred A., Metcalf, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888486/
https://ncbi.nlm.nih.gov/pubmed/20416511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2010.03.007
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