A highly attenuated recombinant human respiratory syncytial virus lacking the G protein induces long-lasting protection in cotton rats

BACKGROUND: Respiratory syncytial virus (RSV) is a primary cause of serious lower respiratory tract illness for which there is still no safe and effective vaccine available. Using reverse genetics, recombinant (r)RSV and an rRSV lacking the G gene (ΔG) were constructed based on a clinical RSV isolat...

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Autors principals: Widjojoatmodjo, Myra N, Boes, Jolande, van Bers, Marleen, van Remmerden, Yvonne, Roholl, Paul JM, Luytjes, Willem
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887800/
https://ncbi.nlm.nih.gov/pubmed/20525213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-114
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