Infection-enhancing lipopeptides do not improve intranasal immunization of cotton rats with a delta-G candidate live-attenuated human respiratory syncytial virus vaccine

Development of live-attenuated human respiratory syncytial virus (HRSV) vaccines has proven to be difficult. Several vaccine candidates were found to be over-attenuated and displayed limited immunogenicity. Recently, we identified three synthetic cationic lipopeptides that enhanced paramyxovirus inf...

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Hlavní autoři: Tien Nguyen, D, Boes, Jolande, van Amerongen, Geert, van Remmerden, Yvonne, Yüksel, Selma, Guichelaar, Teun, Osterhaus, Albert DME, de Swart, Rik L
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
Short Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162065/
https://ncbi.nlm.nih.gov/pubmed/23955280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.26096
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