An improved respiratory syncytial virus neutralization assay based on the detection of green fluorescent protein expression and automated plaque counting

BACKGROUND: Virus neutralizing antibodies against respiratory syncytial virus (RSV) are considered important correlates of protection for vaccine evaluation. The established plaque reduction assay is time consuming, labor intensive and highly variable. METHODS: Here, a neutralization assay based on...

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Main Authors: van Remmerden, Yvonne, Xu, Fang, van Eldik, Mandy
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
Assuntos:
Methodology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514128/
https://ncbi.nlm.nih.gov/pubmed/23114196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-253
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