An improved respiratory syncytial virus neutralization assay based on the detection of green fluorescent protein expression and automated plaque counting

BACKGROUND: Virus neutralizing antibodies against respiratory syncytial virus (RSV) are considered important correlates of protection for vaccine evaluation. The established plaque reduction assay is time consuming, labor intensive and highly variable. METHODS: Here, a neutralization assay based on...

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Autori principali: van Remmerden, Yvonne, Xu, Fang, van Eldik, Mandy
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
Soggetti:
Methodology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514128/
https://ncbi.nlm.nih.gov/pubmed/23114196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-253
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