Revisiting the loading dose of amikacin for patients with severe sepsis and septic shock

INTRODUCTION: It has been proposed that doses of amikacin of >15 mg/kg should be used in conditions associated with an increased volume of distribution (V(d)), such as severe sepsis and septic shock. The primary aim of this study was to determine whether 25 mg/kg (total body weight) of amikacin i...

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Dettagli Bibliografici
Autori principali: Taccone, Fabio Silvio, Laterre, Pierre-François, Spapen, Herbert, Dugernier, Thierry, Delattre, Isabelle, Layeux, Brice, De Backer, Daniel, Wittebole, Xavier, Wallemacq, Pierre, Vincent, Jean-Louis, Jacobs, Frédérique
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887170/
https://ncbi.nlm.nih.gov/pubmed/20370907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc8945
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