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Amikacin Monotherapy for Sepsis Caused by Panresistant Pseudomonas aeruginosa

Two patients with severe sepsis due to panresistant Pseudomonas aeruginosa, deteriorating despite therapy with colistin and β-lactams, were cured with a high daily dose (25 to 50 mg/kg) of amikacin to obtain a peak/MIC ratio of at least 8 to 10 (MIC = 16 μg/ml). Concomitant use of continuous venoven...

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Detalhes bibliográficos
Main Authors: Layeux, Brice, Taccone, Fabio Silvio, Fagnoul, David, Vincent, Jean-Louis, Jacobs, Frédérique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976156/
https://ncbi.nlm.nih.gov/pubmed/20823287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00441-10
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