n-6 Polyunsaturated Fatty Acids Enhance the Activities of Ceftazidime and Amikacin in Experimental Sepsis Caused by Multidrug-Resistant Pseudomonas aeruginosa

Recent in vitro and ex vivo studies disclosed an enhancement of the activity of antimicrobials on multidrug-resistant Pseudomonas aeruginosa by n-6 polyunsaturated fatty acids (PUFAS); therefore their effect was evaluated in experimental sepsis in 60 rabbits. Solutions of gamma-linolenic acid (GLA)...

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Autores principales: Giamarellos-Bourboulis, Evangelos J., Mouktaroudi, Maria, Adamis, Theodoros, Koussoulas, Vassilios, Baziaka, Fotini, Perrea, Despina, Karayannacos, Panayotis E., Giamarellou, Helen
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC529197/
https://ncbi.nlm.nih.gov/pubmed/15561848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.12.4713-4717.2004
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