Revisiting the loading dose of amikacin for patients with severe sepsis and septic shock

INTRODUCTION: It has been proposed that doses of amikacin of >15 mg/kg should be used in conditions associated with an increased volume of distribution (V(d)), such as severe sepsis and septic shock. The primary aim of this study was to determine whether 25 mg/kg (total body weight) of amikacin i...

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Bibliografiska uppgifter
Huvudupphovsmän: Taccone, Fabio Silvio, Laterre, Pierre-François, Spapen, Herbert, Dugernier, Thierry, Delattre, Isabelle, Layeux, Brice, De Backer, Daniel, Wittebole, Xavier, Wallemacq, Pierre, Vincent, Jean-Louis, Jacobs, Frédérique
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2010
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887170/
https://ncbi.nlm.nih.gov/pubmed/20370907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc8945
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