Revisiting the loading dose of amikacin for patients with severe sepsis and septic shock

INTRODUCTION: It has been proposed that doses of amikacin of >15 mg/kg should be used in conditions associated with an increased volume of distribution (V(d)), such as severe sepsis and septic shock. The primary aim of this study was to determine whether 25 mg/kg (total body weight) of amikacin i...

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Autores principales: Taccone, Fabio Silvio, Laterre, Pierre-François, Spapen, Herbert, Dugernier, Thierry, Delattre, Isabelle, Layeux, Brice, De Backer, Daniel, Wittebole, Xavier, Wallemacq, Pierre, Vincent, Jean-Louis, Jacobs, Frédérique
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887170/
https://ncbi.nlm.nih.gov/pubmed/20370907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc8945
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