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HERG1 channelopathies
Human ether a go-go-related gene type 1 (hERG1) K(+) channels conduct the rapid delayed rectifier K(+) current and mediate action potential repolarization in the heart. Mutations in KCNH2 (the gene that encodes hERG1) causes LQT2, one of the most common forms of long QT syndrome, a disorder of cardi...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886309/ https://ncbi.nlm.nih.gov/pubmed/20544339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-009-0758-8 |
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