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HERG1 Channel Agonists and Cardiac Arrhythmia

Type 1 human ether-a-go-go-related gene (hERG1) potassium channels are a key determinant of normal repolarization of cardiac action potentials. Loss of function mutations in hERG1 channels cause inherited long QT syndrome and increased risk of cardiac arrhythmia and sudden death. Many common medicat...

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Detalles Bibliográficos
Autor Principal: Sanguinetti, Michael
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984452/
https://ncbi.nlm.nih.gov/pubmed/24721650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2013.11.006
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