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Assay Strategies for the Discovery and Validation of Therapeutics Targeting Brugia pahangi Hsp90

The chemotherapy of lymphatic filariasis relies upon drugs such as diethylcarbamazine and ivermectin that largely target the microfilarial stages of the parasite, necessitating continued treatment over the long reproductive life span of the adult worm. The identification of compounds that target adu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Taldone, Tony, Gillan, Victoria, Sun, Weilin, Rodina, Anna, Patel, Pallav, Maitland, Kirsty, O'Neill, Kerry, Chiosis, Gabriela, Devaney, Eileen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886105/
https://ncbi.nlm.nih.gov/pubmed/20559560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000714
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