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Pim1 promotes human prostate cancer cell tumorigenicity and c-MYC transcriptional activity
BACKGROUND: The serine/threonine kinase PIM1 has been implicated as an oncogene in various human cancers including lymphomas, gastric, colorectal and prostate carcinomas. In mouse models, Pim1 is known to cooperate with c-Myc to promote tumorigenicity. However, there has been limited analysis of the...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886047/ https://ncbi.nlm.nih.gov/pubmed/20515470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-248 |
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