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Interactions between Cells with Distinct Mutations in c-MYC and Pten in Prostate Cancer

In human somatic tumorigenesis, mutations are thought to arise sporadically in individual cells surrounded by unaffected cells. This contrasts with most current transgenic models where mutations are induced synchronously in entire cell populations. Here we have modeled sporadic oncogene activation u...

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Detalhes bibliográficos
Main Authors: Kim, Jongchan, Eltoum, Isam-Eldin A., Roh, Meejeon, Wang, Jie, Abdulkadir, Sarki A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697385/
https://ncbi.nlm.nih.gov/pubmed/19578399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000542
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