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Pim1 promotes human prostate cancer cell tumorigenicity and c-MYC transcriptional activity

BACKGROUND: The serine/threonine kinase PIM1 has been implicated as an oncogene in various human cancers including lymphomas, gastric, colorectal and prostate carcinomas. In mouse models, Pim1 is known to cooperate with c-Myc to promote tumorigenicity. However, there has been limited analysis of the...

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Detalhes bibliográficos
Main Authors: Kim, Jongchan, Roh, Meejeon, Abdulkadir, Sarki A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886047/
https://ncbi.nlm.nih.gov/pubmed/20515470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-248
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