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Administration of a Sigma Receptor Agonist Delays MCAO-Induced Neurodegeneration and White Matter Injury

Many pharmacological treatments for stroke have afforded protection in rodent models but failed to show efficacy in clinical trials. This discrepancy may be due to the lack of long-term functional studies. Previously, delayed administration of the sigma receptor agonist 1,3-di-o-tolylguanidine (DTG)...

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Detalhes bibliográficos
Main Authors: Leonardo, Christopher C., Hall, Aaron A., Collier, Lisa A., Green, Suzanne M., Willing, Alison E., Pennypacker, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885737/
https://ncbi.nlm.nih.gov/pubmed/20563232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-009-0005-9
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