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Pro-inflammatory interferon gamma signaling is directly associated with stroke induced neurodegeneration

The delayed immune response to stroke is responsible for the increased neural injury that continues to occur after the initial ischemic event. This delayed immune response has been linked to the spleen, as splenectomy prior to middle cerebral artery occlusion (MCAO) is neuroprotective. Interferon ga...

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Библиографические подробности
Главные авторы: Seifert, Hilary A., Collier, Lisa A., Chapman, Cortney B., Benkovic, Stanley A., Willing, Alison E., Pennypacker, Keith R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209188/
https://ncbi.nlm.nih.gov/pubmed/25104571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-014-9560-2
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