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The spleen contributes to stroke induced neurodegeneration through interferon gamma signaling

Delayed neuronal death associated with stroke has been increasingly linked to the immune response to the injury. Splenectomy prior to middle cerebral artery occlusion (MCAO) is neuroprotective and significantly reduces neuroinflammation. The present study investigated whether splenic signaling occur...

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Detalles Bibliográficos
Publicado en:Metab Brain Dis
Main Authors: Seifert, Hilary A., Leonardo, Christopher C., Hall, Aaron A., Rowe, Derrick D., Collier, Lisa A., Benkovic, Stanley A., Willing, Alison E., Pennypacker, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739736/
https://ncbi.nlm.nih.gov/pubmed/22354752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-012-9283-0
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