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The spleen contributes to stroke induced neurodegeneration through interferon gamma signaling

Delayed neuronal death associated with stroke has been increasingly linked to the immune response to the injury. Splenectomy prior to middle cerebral artery occlusion (MCAO) is neuroprotective and significantly reduces neuroinflammation. The present study investigated whether splenic signaling occur...

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Dades bibliogràfiques
Publicat a:Metab Brain Dis
Autors principals: Seifert, Hilary A., Leonardo, Christopher C., Hall, Aaron A., Rowe, Derrick D., Collier, Lisa A., Benkovic, Stanley A., Willing, Alison E., Pennypacker, Keith R.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739736/
https://ncbi.nlm.nih.gov/pubmed/22354752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-012-9283-0
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