Cargando...

Titers of lentiviral vectors encoding shRNAs and miRNAs are reduced by different mechanisms that require distinct repair strategies

RNAi-based gene therapy is a powerful approach to treat viral infections because of its high efficiency and sequence specificity. The HIV-1-based lentiviral vector system is suitable for the delivery of RNAi inducers to HIV-1 susceptible cells due to its ability to transduce nondividing cells, inclu...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Liu, Ying Poi, Vink, Monique A., Westerink, Jan-Tinus, Ramirez de Arellano, Eva, Konstantinova, Pavlina, Ter Brake, Olivier, Berkhout, Ben
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885682/
https://ncbi.nlm.nih.gov/pubmed/20498457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1887910
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!