Llwytho...

Modulation of the Active Complex Assembly and Turnover Rate by Protein–DNA Interactions in Cre–LoxP Recombination,

Cre promotes recombination at the 34 bp LoxP sequence. Substitution of a critical C-G base pair in LoxP with an A-T base pair, to give LoxAT, reduced Cre binding in vitro and abolished recombination in vivo. We demonstrated that LoxAT can be recombined in vitro. However, Cre discriminates against th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Martin, Shelley S., Chu, Victor C., Baldwin, Enoch
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885442/
https://ncbi.nlm.nih.gov/pubmed/12779336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0272306
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