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Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine

BACKGROUND: Griseofulvin, an antifungal drug, has recently been shown to inhibit proliferation of various types of cancer cells and to inhibit tumor growth in athymic mice. Due to its low toxicity, griseofulvin has drawn considerable attention for its potential use in cancer chemotherapy. This work...

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מידע ביבליוגרפי
Main Authors: Rathinasamy, Krishnan, Jindal, Bhavya, Asthana, Jayant, Singh, Parminder, Balaji, Petety V, Panda, Dulal
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885362/
https://ncbi.nlm.nih.gov/pubmed/20482847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-213
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