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E93R Substitution of Escherichia coli FtsZ Induces Bundling of Protofilaments, Reduces GTPase Activity, and Impairs Bacterial Cytokinesis

Recently, we found that divalent calcium has no detectable effect on the assembly of Mycobacterium tuberculosis FtsZ (MtbFtsZ), whereas it strongly promoted the assembly of Escherichia coli FtsZ (EcFtsZ). While looking for potential calcium binding residues in EcFtsZ, we found a mutation (E93R) that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jaiswal, Richa, Patel, Ronak Y., Asthana, Jayant, Jindal, Bhavya, Balaji, Petety V., Panda, Dulal
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951251/
https://ncbi.nlm.nih.gov/pubmed/20667825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.138719
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