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E93R Substitution of Escherichia coli FtsZ Induces Bundling of Protofilaments, Reduces GTPase Activity, and Impairs Bacterial Cytokinesis

Recently, we found that divalent calcium has no detectable effect on the assembly of Mycobacterium tuberculosis FtsZ (MtbFtsZ), whereas it strongly promoted the assembly of Escherichia coli FtsZ (EcFtsZ). While looking for potential calcium binding residues in EcFtsZ, we found a mutation (E93R) that...

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Detalhes bibliográficos
Main Authors: Jaiswal, Richa, Patel, Ronak Y., Asthana, Jayant, Jindal, Bhavya, Balaji, Petety V., Panda, Dulal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951251/
https://ncbi.nlm.nih.gov/pubmed/20667825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.138719
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