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Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine

BACKGROUND: Griseofulvin, an antifungal drug, has recently been shown to inhibit proliferation of various types of cancer cells and to inhibit tumor growth in athymic mice. Due to its low toxicity, griseofulvin has drawn considerable attention for its potential use in cancer chemotherapy. This work...

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Main Authors: Rathinasamy, Krishnan, Jindal, Bhavya, Asthana, Jayant, Singh, Parminder, Balaji, Petety V, Panda, Dulal
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885362/
https://ncbi.nlm.nih.gov/pubmed/20482847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-213
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