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Dynein Light Chain 1 (LC8) Association Enhances Microtubule Stability and Promotes Microtubule Bundling

Dynein light chain 1 (LC8), a highly conserved protein, is known to bind to a variety of different polypeptides. It functions as a dimer, which is inactivated through phosphorylation at the Ser-88 residue. A loss of LC8 function causes apoptosis in Drosophila embryos, and its overexpression induces...

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Bibliographische Detailangaben
Hauptverfasser: Asthana, Jayant, Kuchibhatla, Anuradha, Jana, Swadhin Chandra, Ray, Krishanu, Panda, Dulal
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504791/
https://ncbi.nlm.nih.gov/pubmed/23038268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.394353
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