Limitations of Peptide Retro-inverso Isomerization in Molecular Mimicry

A retro-inverso peptide is made up of d-amino acids in a reversed sequence and, when extended, assumes a side chain topology similar to that of its parent molecule but with inverted amide peptide bonds. Despite their limited success as antigenic mimicry, retro-inverso isomers generally fail to emula...

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Bibliografiske detaljer
Main Authors: Li, Chong, Pazgier, Marzena, Li, Jing, Li, Changqing, Liu, Min, Zou, Guozhang, Li, Zhenyu, Chen, Jiandong, Tarasov, Sergey G., Lu, Wei-Yue, Lu, Wuyuan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885236/
https://ncbi.nlm.nih.gov/pubmed/20382735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.116814
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