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Direct and Coordinate Regulation of ATP-binding Cassette Transporter Genes by Myc Factors Generates Specific Transcription Signatures That Significantly Affect the Chemoresistance Phenotype of Cancer Cells

Increased expression of specific ATP-binding cassette (ABC) transporters is known to mediate the efflux of chemotherapeutic agents from cancer cells. Therefore, establishing how ABC transporter genes are controlled at their transcription level may help provide insight into the role of these multifac...

সম্পূর্ণ বিবরণ

সংরক্ষণ করুন:
গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Porro, Antonio, Haber, Michelle, Diolaiti, Daniel, Iraci, Nunzio, Henderson, Michelle, Gherardi, Samuele, Valli, Emanuele, Munoz, Marcia A., Xue, Chengyuan, Flemming, Claudia, Schwab, Manfred, Wong, Jason H., Marshall, Glenn M., Della Valle, Giuliano, Norris, Murray D., Perini, Giovanni
বিন্যাস: Artigo
ভাষা:Inglês
প্রকাশিত: American Society for Biochemistry and Molecular Biology 2010
বিষয়গুলি:
অনলাইন ব্যবহার করুন:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885232/
https://ncbi.nlm.nih.gov/pubmed/20233711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.078584
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