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In vivo transcriptional regulation of N-Myc target genes is controlled by E-box methylation

N-Myc is a transcription factor that forms heterodimers with the protein Max and binds gene promoters by recognizing a DNA sequence, CACGTG, called E-box. The identification of N-myc target genes is an important step for understanding N-Myc biological functions in both physiological and pathological...

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Detalles Bibliográficos
Main Authors: Perini, Giovanni, Diolaiti, Daniel, Porro, Antonio, Della Valle, Giuliano
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184034/
https://ncbi.nlm.nih.gov/pubmed/16093321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409097102
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